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1,2,4-Butanetriol is a clear or slightly yellow, odorless, hydroscopic, flammable, viscous, liquid. It is an alcohol with three hydrophilic alcoholic hydroxyl groups. It is similar to glycerol and erythritol. It is chiral, with two possible enantiomers.
1,2,4-Butanetriol is used in the manufacture of butanetriol trinitrate (BTTN), an important military propellant.
1,2,4-Butanetriol is also used as a precursor for two cholesterol-lowering drugs, Crestor and Zetia, which are derived from D-3,4-dihydroxybutanoic acid, by using 3-hydroxy-gamma-butyrolactone as a chiral synthon .
(Niu, W (2003). "Microbial synthesis of the energetic material precursor 1,2,4-butanetriol". Am. Chem. Soc. 125 (43): 12998–12999. doi:10.1021/ja036391+. "Biosynthetic Pathways". Retrieved 24 November 2010.)
It is as one of the monomers for manufacture of some polyesters and as a solvent.
Typical Properties :
Formula: C4H10O3
CAS# 3068-00-6
Assay: 96 – 97%
Color/Form: Clear yellow to slightly brown liquid
Odor: Odorless
Specific Gravity: 1.190 – 1.193
Formula Weight: 106.12
Melting Point: -20oC
Boiling Point: 190 – 191oC (at 18 torr)
Flash Point: 188oC
Refractive Index: 1.471 – 1.476 n20/D
Hydroscopic: Yes
This item is export controlled in larger quantities and may require an “end-use statement”.